How do we synthesize carbon-carbon bonds

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Organometallic compounds 30 min.

This learning unit describes the synthesis, structure and reactions of organometallic compounds using the example of lithium, magnesium and Gilman reagents.

The Grignard reaction 20 min.

It is one of the classic organometallic reactions for building CC bonds in synthetic organic chemistry and, thanks to its wealth of variants, opens up the possibility of converting a large number of different functional groups into others - the Grignard reaction, which has not been used for over 100 years is to be imagined without the laboratories.

Palladium-Catalyzed Cross-Coupling and Related Reactions 15 minutes.

For the organic-synthetic chemist, reactions to build bonds between carbon atoms are an important tool of the trade. They allow him to assemble small molecules into large compounds, e.g. B. to synthesize new active ingredients or to produce naturally occurring substances in the laboratory. The particularly interesting C-C linkage reactions include the palladium-catalyzed cross-couplings and the Heck reaction, which in their many variants open up numerous new synthetic possibilities.